Bimatoprost (marketed in the U.S., Canada and Europe by Allergan, under the trade names Latisse, Careprost and Lumigan) is a prostaglandin analog/prodrug used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. It reduces intraocular pressure (IOP) by increasing the outflow of aqueous fluid from the eyes. It has also been used and prescribed off-label to lengthen eyelashes. In December 2008, this use was approved by the U.S. Food and Drug Administration (FDA); the cosmetic formulation of bimatoprost is sold as Latisse. Recently, at least three case series have suggested that bimatoprost has the ability to reduce adipose tissue.


Careprost Latisse Cosmetic utilization

In patients utilizing ophthalmic prostaglandins, for example, travoprost and latanoprost, and in addition prostamides like bimatoprost, it has been episodically noted that there had been a build in measurement, thickness and length of eyelashes. Allergan has started clinical trials researching the utilization of Lumigan as a nonessential medication. On December 5, 2008, the FDA Dermatologic and Ophthalmic Drugs Advisory Committee voted to support bimatoprost for the nonessential utilization of obscuring and extending eyelashes. The restorative term for this is treatment of hypotrichosis, nonetheless, the FDA endorsement is for simply corrective purposes.

As indicated by Allergan`s bundle marking, clients of its Latisse nonessential item didn’t create darker irises in clinical studies; be that as it may, patients ought to be prompted about the potential for expanded tan iris pigmentation which is prone to be lasting.

A few beauty care products organizations have discharged items focused around prostaglandin analogs, as non-medication beatufiers.

– Age Intervention Eyelash by Jan Marini Skin Research

– Revitalash by Athena Cosmetics Corp.

– MD Lash Factor by Photomedex Inc.

These organizations have been sued by Allergan for patent encroachment. The FDA has seized Age Intervention Eyelash as an unapproved and misbranded medication in light of the fact that Jan Marini Skin Research advertised it as something that expands eyelash development and on the grounds that it is defiled with bimatoprost.

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